T cell senescence occurs in the TME, affecting cancer prognosis and immunotherapy efficacy. The TME induces T cell senescence ...

Lymphoid-derived conventional dendritic cells (L-cDCs) may play a unique function associated with immune suppression and ...

In ALS, the loss of certain proteins turns off a gene called UNC13A that needs to stay active for nerve cell communication, a ...

By offering unprecedented insights into how senescent cells function within living tissues and affect surrounding cells, the research lays a foundation for future studies and therapeutic ...

Dr. Hamilton Se-Hwee Oh at Mount Sinai in New York pioneers research linking differential organ aging to depression and ...

The tumor microenvironment (TME) represents a highly complex system that encompasses cellular components (such as cancer cells, stromal cells, and immune cells) and non-cellular components (such as ...

Scientists create smart cells that administer automatic treatments from inside the human body, reacting within seconds to ...

In a surprising twist on plant genetics, researchers have identified a mitochondrial protein that directly regulates wood ...

The membrane-bound organelle appears to play a huge role in helping cells sort, discard, and recycle their contents. It's ...

A new study led by researchers at the University of Rochester Medical Center (URMC) found that early-life exposure to ...

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing ...

Epigenetics often reflect environmental exposures — such as stress, trauma, nutrition or caregiving. But they’re not necessarily permanent “scars”. Many are dynamic and can shift with changing ...