A ginger-derived molecule known as EMC shuts down a cancer's fat-making machinery causing it to activate backup systems and ...

In addition, CDC25 phosphatases must be inactivated in response to checkpoint activation to stop cell cycle progression and allow the cell time to either repair the DNA or initiate apoptosis.

The timing of immunotherapy initiation is not a significant factor in the outcomes of patients with extensive-stage small ...

Incyte today announced that primary results from the Phase 3 POD1UM-303/InterAACT 2 trial of retifanlimab (Zynyz®), a humanized monoclonal antibody targeting programmed death receptor-1 (PD-1), in ...

Poster Title: ARV-393, a PROteolysis TArgeting Chimera (PROTAC) BCL6 Degrader, is Efficacious in Preclinical Models of ...

CHAF1B, a histone chaperone component of the chromatin assembly factor-1 complex, is overexpressed in multiple cancers and ...

Programmed cell death serves as a critical defense mechanism during viral infection. The kinases RIPK1 and RIPK3, central ...

Disrupting the G-loop cycle causes transcriptome dysregulation and genome instability, revealing key role in cell survival ...

Scientists have uncovered how exercise directly influences brain health in Alzheimer's disease by pinpointing the exact brain ...

A new Phase 2 trial suggests that using an electric field device placed on the scalp, along with immunotherapy and ...

Unsupervised neighbourhood detection based on the spatial interaction of immune cells identified three immune architectures with differing involvement of immune cells and immune checkpoints dominated ...