Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Priya Hays, Hays Documentation Specialists, discusses innovations and advancements in the development of personalized cancer ...

This work indicates that introduction of telomerase into normal human somatic cells does not lead to growth transformation, does not bypass cell–cycle induced checkpoint controls and does not ...

Recent advances in immunotherapy have revolutionized the treatment of breast and gynecological cancers, and current ...

Extended cash runway into late 2027, beyond a potentially registration-enabling azenosertib data readout from DENALI Part 2 Planned workforce reduction of approximately 40% of employees Corporate ...

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

or aberrant DNA damage checkpoints. Although replication stress can lead to DNA damage, cell cycle arrest, interferon (IFN) signaling, and senescence or cell death, some cancer cells can evolve to ...

Results from DENALI Part 1b show an Objective Response Rate (ORR) of ~35% in response-evaluable, heavily-pretreated patients with Cyclin E1+ ...

Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory for Digestive Health, National Clinical Research Center for Digestive Disease, Beijing ...

We’re in Chengdu, the capital of China’s Sichuan region, to visit Leenzee, the studio co-founded by Xia in 2016 – and to ...

To counteract these challenges, novel strategies aim to restore the cancer immunity cycle. One approach involves directly injecting unadjuvanted influenza vaccines or drug-loaded oncolytic viruses ...