factors involved in maintenance of cell cycle checkpoints, and proteins required for apoptosis induction. The types of genetic alterations leading to pRb inactivity most often involve frameshifts ...

The replication fork is more than just a means for DNA duplication. It is connected to a checkpoint system that keeps the genome intact and prevents cancer. Aa Aa Aa Eukaryotic genomes are ...

One poster demonstrating cell-free DNA molecular response as a potential surrogate endpoint to measure clinical efficacy of azenosertib in ...

Damage-Induced Checkpoint Activation Regulation of the mammalian cell cycle is accomplished by multiple protein-protein interactions and phosphorylation events, which promote the progression from ...