Two major cohorts were included. COPDGene enrolled 10,305 participants at 21 sites in the United States between 2007 and 2011, with follow-up through 2022. CanCOLD enrolled 1,561 participants ...

An estimated 70% of U.S. patients with inadequately controlled COPD despite triple inhaled therapy have a blood eosinophil count at that level. Two positive phase III trials -- MATINEE and METREX ...

Adding mepolizumab to inhaled triple therapy significantly improved exacerbation outcomes compared with placebo in adults with chronic obstructive pulmonary disease (COPD), based on data from the ...

May 23, 2025 -- The FDA has approved the asthma drug Nucala for adults with chronic obstructive pulmonary disease (COPD). It is the second biologic therapy approved for the condition, following ...

This corrects the date that the BMO Capital note was published. Shares of Regeneron Pharmaceuticals Inc. were having their worst day in more than a decade on Friday after a shocking failure in a ...

Accordingly, the interleukin-5-targeting antibody therapy will therefore be available as an add-on maintenance treatment in the U.S. specifically for adults with inadequately controlled COPD and ...

Mepolizumab targets IL-5, addressing eosinophilic inflammation in 20%-40% of COPD patients, marking its fifth US indication. The phase 3 MATINEE trial showed a 21% reduction in annualized moderate ...

While GSK’s Nucala may not have earned the distinction of becoming the first FDA approved biologic for chronic obstructive pulmonary disease (COPD), the British drugmaker is confident its IL-5 ...

COPD is a group of progressive lung diseases that includes emphysema and chronic bronchitis. Despite affecting an estimated 32 million people in the United States, as many as half are unaware they ...

SAN FRANCISCO — Patients with COPD and type 2 inflammation receiving mepolizumab vs. placebo had decreased moderate and severe exacerbation rates and fewer ED visits per exacerbation at 104 ...

Viz.ai's recent partnership with Sanofi and Regeneron Pharmaceuticals brings AI technology to aid in the management of COPD patients, enhancing the healthcare process. Throughout the past month ...

If you or your partner are living with chronic obstructive pulmonary disease, you may be wondering what effect COPD will have on your sexuality. Will sex be possible? Will it be safe? Satisfying?