Cutting a single amino acid from the diet caused rapid, drastic weight loss in mice by converting white fat into calorie-burning brown fat. The study reveals a powerful new mechanism for weight loss ...

A biotech startup based in Uruguay has successfully completed early-stage human trials for a first-in-class drug that targets ...

Researchers have uncovered hidden biological changes in fat tissue during weight loss, including cellular cleanup and energy-boosting recycling mechanisms. Scientists have, for the first time, closely ...

The first human-tested weight-loss drug that burns calories through creatine-based heat generation, without reducing appetite, has successfully completed its Phase I trial.

When brown fat — calorie-burning adipose tissue once thought to exist only in infants — was discovered in adults 15 years ago, obesity medicine researchers started searching for ways to help ...

Weight loss reverses much of this damage, especially senescence in fat and vascular cells, but leaves some immune dysfunction behind.

Now, Kusminski and her team have found that GIPR activation in the fat tissue of mice enhances energy expenditure and triggers weight loss. 3 Their findings, published in Cell Metabolism, highlight ...

It suggests that the weight loss does more than shave off pounds — it changes fat on a cellular level, rewiring how the tissue is metabolized and maybe even "rejuvenating" it. The research also offers ...

In a long-term process called thermogenesis, brown fat cells create heat to keep the body warm. When you are cold for a long enough time, the white fat cells are forced to start acting like brown fat.

Struggling to Lose Weight, and Keep It Off? That Might Be Because Research Shows Fat Cells ‘Remember’ Being Fat Making the weight loss market even more attractive for entrepreneurs who find ...

Fat cells indeed have a memory of being obese, which can make it easier to regain weight and stay in a state that promotes inflammation and metabolic issues, confirmed Gretchen Zimmermann ...

For example, a 2024 analysis in The Lancet Diabetes & Endocrinology found that muscle loss with GLP-1 receptor agonists (GLP-1 RAs) ranges from 25% to 39% of total weight lost over 36-72 weeks.