Research in Dr. Schafer's Brain and Systemic Aging Lab at Mayo Clinic focuses on how aging changes cell identities, tissue composition, and brain health and function.

Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer’s disease, the researchers observed how the loss of ADGRG1 led to the rapid buildup of ...

Method combines genomics technologies with computational modeling to predict changes in multicellular behavior, such as cell communication.

Funded primarily by the Jayne Koskinas Ted Giovanis Foundation and the National Institutes of Health, and leveraging prior ...

These Immune Cells Eat Molecular Trash to Keep Alzheimer's at Bay UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer’s, with ...

Chemical chatter from resident bacteria in the gut can hit the brain and nervous system in real time, shaping behavior and ...

Summary: Unlike most tissues, the retina doesn’t summon neutrophils—the body’s typical first responders—when injured. Instead ...

During most eye infections or injuries, neutrophils, immune cells found in the blood, are usually the first line of defense.

The experimental mRNA vaccine developed at the University of Florida has shown the ability to supercharge the immune system ...

MS may increase the risk of Alzheimer's disease, possibly due to changes in the activity of immune T-cells, a new genetic ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other ...

Cells in key brain regions involved in Parkinson's retain a "memory" of pesticide exposure that disrupts gene expression, new ...