Research in Dr. Schafer's Brain and Systemic Aging Lab at Mayo Clinic focuses on how aging changes cell identities, tissue composition, and brain health and function.

Without the receptor, ADGRG1, the microglia barely nibbled on the toxic protein. Using a mouse model of Alzheimer’s disease, the researchers observed how the loss of ADGRG1 led to the rapid buildup of ...

Method combines genomics technologies with computational modeling to predict changes in multicellular behavior, such as cell communication.

Funded primarily by the Jayne Koskinas Ted Giovanis Foundation and the National Institutes of Health, and leveraging prior ...

Advance could usher in new era of research for schizophrenia, autism, Alzheimer's, and other neurological diseases ...

A breakthrough AI system is revolutionizing cancer immunotherapy by enabling scientists to design protein-based keys that ...

Subtle differences in an mRNA sequence enables a ribosome to produce more or less of a certain protein. A new AI model called ...

Ben Trotman, diagnosed with terminal glioblastoma in 2022, experienced a complete remission after receiving ipilimumab before standard treatment as pa ...

These Immune Cells Eat Molecular Trash to Keep Alzheimer's at Bay UCSF scientists have discovered how microglia engulf and break down amyloid beta, a protein that builds up in Alzheimer’s, with ...

Chemical chatter from resident bacteria in the gut can hit the brain and nervous system in real time, shaping behavior and ...

Summary: Unlike most tissues, the retina doesn’t summon neutrophils—the body’s typical first responders—when injured. Instead ...

During most eye infections or injuries, neutrophils, immune cells found in the blood, are usually the first line of defense.