The GINA 2025 asthma update includes new guidance on T2 biomarkers, asthma in young children, and climate change.

Microbiome traits are likely regulated by trichostatin A, nuclear factor-κB, and CCAAT/enhancer-binding protein (CEBP) in asthma exacerbations, a new study suggests In a study on human genetics ...

Children with uncontrolled, moderate to severe asthma used dupilumab or placebo for 52 weeks. The treatment group had significant decreases in annualized exacerbation rates compared with the ...

as measured by the 5-item Asthma Control Questionnaire (ACQ-5), was significantly improved by dupilumab, regardless of exacerbation history, according to research presented at the 2018 Annual ...

Asthma diagram, lungs The primary outcome was to compare dupilumab, benralizumab, and mepolizumab in patients with at least 2 pre-index exacerbations. Asthma exacerbations and systemic ...

Dupilumab significantly reduced the risk of exacerbations compared with placebo in children with moderate to severe asthma, regardless of exacerbation history. Dupilumab was shown to consistently ...

There is no evidence that increasing the dose of inhaled corticosteroids at the onset of an asthma exacerbation, as part of a patient-initiated action plan, reduces the need for rescue oral ...

Host factors probably contribute to the risk of asthma inception and exacerbation, and these contributions may also vary with respect to early- versus adult-onset disease. This review discusses ...

Inhalers In patients using as-needed short-acting beta2-agonists, how are exacerbations associated with asthma control, maintenance adherence, and disease severity? Risk for exacerbations exists ...

PHOENIX, Arizona — In a 15-month phase 4 trial, an inexpensive intervention that can be explained in a single office visit reduced severe exacerbations and improved asthma control in patient ...

The annualized rate of severe asthma exacerbations was lower with albuterol–budesonide than with albuterol (0.15 vs. 0.32; rate ratio, 0.47; 95% CI, 0.34 to 0.64), as was the mean annualized ...