WEDNESDAY, June 25, 2025 (HealthDay News) -- For women with breast cancer (BC), BRCA mutations are associated with increased risk of developing breast implant–associated anaplastic large cell ...

Activating Janus kinase (JAK) mutations occur only in a minority of T-cell malignancies, which would appear to limit the clinical application of JAK inhibition for these diseases. Our study suggests ...

Background Anaplastic large cell lymphomas are rare but aggressive T-cell lymphomas. About 60-80 % of cases carry a gene fusion of the ALK gene, which drives tumour growth.

Cemacabtagene ansegedleucel, an allogeneic chimeric antigen receptor (CAR) T-cell therapy, is being investigated in relapsed/refractory large B-cell lymphoma.

The FDA has approved ensartinib in adult patients with anaplastic lymphoma kinase (ALK)–positive locally advanced or metastatic non–small cell lung cancer (NSCLC) naive to ALK treatment.

Anaplastic large-cell lymphoma (ALCL) is a rare type of cancer of white blood cells.

A collaboration between scientists from St. Jude Children's Research Hospital and Dana-Farber Cancer Institute uncovered four proteins that govern the identity of anaplastic large cell lymphoma ...

Activation of anaplastic lymphoma kinase (ALK) through chromosome rearrangement, amplification, mutation or deregulated expression has been found in anaplastic large cell lymphomas, inflammatory ...

Anaplastic large cell lymphoma (ALCL) is a rare subtype of non-Hodgkin lymphoma and a form of T-cell lymphoma. Read about symptoms, diagnosis, and treatment.