Lipid kinases are enzymes that play a critical role in both cell signalling and membrane trafficking by phosphorylating lipid ...

The enzyme AMPD1 plays a key role in muscle energy production and normal muscular function. Loss of AMPD1 activity due to ...

Lipid kinases are enzymes that play a critical role in both cell signaling and membrane trafficking by phosphorylating lipid ...

This study identifies astrocyte-intrinsic mechanisms by which the LRRK2 G2019S, a mutation linked to familial Parkinson's disease, disrupts synaptic integrity in the anterior cingulate cortex. The ...

Approach and Results— We tested the hypothesis that heme in pathologically relevant concentrations activates the ATF1–Mhem pathway via 5′-AMP–activated protein kinase (AMPK) in primary human ...

Emerging research suggests that a daily coffee habit may contribute to longevity and improved aging. Beyond alertness, ...