Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

Cancer Molecular Therapeutics Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 N Torrey Pines Rd, La Jolla, California 92037, United States ...

This article explores methods to enhance efficiency in the drug discovery and development pipeline, focusing on optimizing ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

A new deep learning model, MUNIS, can rapidly identify HLA-binding, immunogenic and immunodominant ... neoantigen and its WT counterpart, the allosteric formation of a peptide-dependent dynamic ...

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...

Researchers at Durham University have achieved a major advancement in understanding how proteins bind metals inside cells, a process crucial to life. The study, published in Nature Communications, ...

Now it is shown that allosteric signalling membrane proteins can be engineered through such networks, revealing a broader space of designable protein interactions and functions. Here the authors ...

Chief R&D and commercial officer Najat Khan, PhD, tells GEN Edge company aims to improve design of studies, accelerate enrollment, and enhance evidence generation.

Click to share on Facebook (Opens in new window) Click to share on X (Opens in new window) Click to share on Reddit (Opens in new window) The top affair sites might cater to you in ways you can ...

After hours: January 31 at 7:46:04 PM EST Loading Chart for SITC ...