Small-conductance calcium-activated potassium channel 2 (SK2) serves a variety of biological functions by coupling intracellular calcium dynamics with membrane potential. SK2 modulators are in ...

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the ...

ALKBH1 is a genomic DNA 6mA demethylase that preferentially removes 6mA in bubbled/bulged DNA and ssDNA, instead of dsDNA.

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the ...

During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the ...

Background Steatotic liver disease-related hepatocellular carcinoma (SLD-HCC), a rising global challenge, is characterised by ...

Abstract Summary Pharmacological enhancement of endoplasmic reticulum (ER) proteostasis is an attractive strategy to mitigate pathology linked to etiologically-diverse protein misfolding diseases.

Arcellx, Inc. advances anito-cel CAR-T therapy for relapsed/refractory multiple myeloma. Click for ACLX pivotal trials, FDA ...