Myosin in muscles behaves in a unique way, which might explain why muscles have such strong contractile power. A cartoon showing the asymmetry in the weak binding between myosin and actin that biases ...

Abstract The molecular interaction between smooth muscle (SM) myosin and actin in the corpus cavernosum (CC) determines the erectile state of the penis.

Therefore, the effect of actin on the structure of myosin is poorly understood. Here we show that the swing of smooth muscle myosin lever arm requires both ADP and actin.

When a muscle cell is activated by its nerve cell, the interaction of actin and myosin generates force through so-called power strokes.

Muscles contract by sliding between thick filaments of myosin and thin filaments of actin. But there has been a longstanding controversy about the dynamics of this molecular machine.

While their functions are diverse, myosins are similar in structure. NMII is so much like cardiac myosin, which keeps the ...

This study explores the use of polarized second-harmonic generation (pSHG) to investigate myosin conformation in the relaxed state, differentiating between the actin-available, disordered (ON) state ...

Does protein build muscle? The answer to this question is a resounding, ‘yes’. Muscle tissue is composed of a repeating structure of two protein filaments: myosin and actin. Myosin and actin ...

"Whenever cells move or divide, actin is involved, like its partner myosin." "But in the nucleus," de Lanerolle said, "actin acts instead like a binding protein.

In healthy muscle, small threadlike components called actin and myosin neatly line up next to each other. With DOMs, “all of the actin and myosin are jumbled together,” Dr. Reiner says.