Small-conductance calcium-activated potassium channel 2 (SK2) serves a variety of biological functions by coupling intracellular calcium dynamics with membrane potential. SK2 modulators are in ...

The transparent oil-continuous systems are familiar as 'soluble-oil' and similar concentrates: the essential conditions for their formation are (1) highsoap/water ratio, (2) the presence of an ...

Amino acids play a fundamental role in regulating how cells respond to drugs. These molecules, which form proteins, act like ...

SMC (structural maintenance of chromosomes) protein complexes are ring-shaped molecular motors essential for genome folding. Despite recent progress, the detailed molecu ...

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...