Explore the functional characterization of 3D neurospheres in healthy and Alzheimer’s models using iPSC-derived neurons.

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The therapeutic molecules self-assemble into nanofibers, which bond to the neuron-killing proteins. Now trapped, the toxic proteins can no longer enter neurons and instead harmlessly degrade.

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Designated as an ACS Editor’s Choice article, the study is published in the Journal of the American Chemical Society ("Supramolecular copolymerization of glycopeptide amphiphiles and amyloid peptides ...

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The study, "Supramolecular copolymerization of glycopeptide amphiphiles and amyloid peptides improves neuron survival," was ... in Stupp's laboratory, is the paper's first author.

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More recently, researchers have begun to explore how to utilize diffusion models to generate 3D data, as doing so has more potential in real-world applications. This requires careful design choices in ...