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New python toolkit automates single-cell lineage tracing, accelerates tumor drug resistance analysis
Researchers at Tsinghua University have unveiled a new Python toolkit for automated single-cell lineage tracing and analysis—featuring rapid barcode QC, clone-size metrics, dynamic Sankey ...
In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That''s where Perturb-Seq comes in-a method ...
Researchers identified a combination of two existing cancer drugs, letrozole and irinotecan, that reversed Alzheimer’s ...
Background Steatotic liver disease-related hepatocellular carcinoma (SLD-HCC), a rising global challenge, is characterised by ...
Ligand-receptor dynamics in heterophily-aware graph neural networks for enhanced cell type prediction from single-cell RNA-seq data ...
Market OutlineThe Global Single Cell Analysis Market is valued at USD 4.90 Billion in 2024 and is projected to attain a value ...
Hippocampal single-cell RNA Atlas of chronic methamphetamine abuse-induced cognitive decline in mice
The authors proposed two hypotheses: first, that methamphetamine induces neuroinflammation, and second, that it alters neuronal stem cell differentiation. These are valuable hypotheses, and the ...
Learn more about the research of Mayo Clinic's Gene Editing and Cellular Engineering Laboratory led by David (Chun-Wei) D.
A new study reveals that neurons in the brain’s memory center, the hippocampus, continue to form well into late adulthood. A ...
Perturb-seq, CROP-seq, and related technologies combine CRISPR/Cas9 and single-cell RNA-sequencing (scRNA-seq) to measure single-cell responses to pooled CRISPR guide RNA libraries (Dixit et al, 2016) ...
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In conclusion, this study utilized multi-level single-cell sequencing to comprehensively characterize the T cell subsets in CML patients, revealing " significant changes in the number and gene ...
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