Without the ability to create cellular models with different mutation loads ... platinum transcription activator-like ...

In neurodegenerative diseases such as Alzheimer's or Parkinson's, proteins accumulate in the body's cells, fold incorrectly ...

Eukaryotic cells cope with starving conditions by eating their own components, a process ... detecting the enzyme's activity in what was known as the microsomal fraction of the cell.

Researchers at Pennington Biomedical Research Center have revealed critical insights into how impaired mitochondrial dynamics ...

Researchers in Cambridge have identified a key enzyme that drives Parkinson’s disease and have shown that blocking it ...

If oxygen is available to the cell then the pyruvate molecules ... As in stage one, the breakdown reactions in this process are catalysed by specific enzymes. Oxygen does not react directly ...

An enzyme called cyclin ... of Molecular & Cellular Biology. The team also found that a broader range of tumors, including both breast and pancreatic cancer models, respond to CDK2 inhibitors ...

Without the ability to create cellular models with different mutation loads ... like effector nucleases (mpTALENs)—specialized enzymes that can selectively target and cleave specific DNA ...

Researchers have revealed critical insights into how impaired mitochondrial dynamics and quality control mechanisms in skeletal muscle influence insulin sensitivity in patients with Type 2 Diabetes, ...