HIV-1 can be successfully treated with long-acting injectable antiretroviral therapy A dual regimen combining the integrase strand transfer inhibitor cabotegravir with the nonnucleoside reverse ...

Recommendation The Canadian Task Force on Preventive Health Care recommends against instrument-based depression screening using a questionnaire with cut-off score to distinguish “screen positive” and ...

Background: In Canada, low awareness of evidence-based interventions for the clinical management of alcohol use disorder exists among health care providers and people who could benefit from care. To ...

Figure 1: (A) Numerous black–brown granules attached to the left eyelashes and eyelids of a 77-year-old woman with phthiriasis palpebrarum. (B) Dermoscopy showed multiple lice and ovoid nits on the ...

Symptoms of diverticulitis may be driven by inflammation rather than infection Contemporary evidence shows that use of antibiotics in uncomplicated cases of diverticulitis neither accelerates recovery ...

BACKGROUND: The Global Burden of Disease Study represents a large and systematic effort to describe the burden of diseases and injuries over the past 3 decades. We aimed to summarize the Canadian data ...

Primary ovarian insufficiency (POI) affects 1% of reproductive-aged women In POI, ovarian follicles become depleted or dysfunctional in people younger than 40 years. Risk factors include family ...

Trichomoniasis is the most common curable sexually transmitted infection worldwide Although trichomoniasis is not a reportable disease, the estimated North American prevalence is 2.8%–3.1% among women ...

A 43-year-old man presents requesting screening for sexually transmitted infections (STIs). His medical history is remarkable for systemic lupus erythematosus (SLE), and he is currently receiving no ...

KEY POINTS In most medical subspecialties, genetic and genomic testing have become a routine part of clinical care. However, access to genetic testing at the patient, provider, and provincial levels ...

Accessibility adaptations like online booking and virtual consultations can reduce care avoidance observed in autistic people. Access to accurate diagnoses and better health outcomes can be supported ...

At large doses used recreationally (300 to > 1500 mg), dextromethorphan and its metabolite dextrophan block N -methyl-d-aspartate receptors, producing dissociative effects similar to those of ...