For hybridization reactions (such as Southern or Northern blots), it is desirable to generate highly specific probes where the label is distributed throughout the nucleic acid.

Whereas qPCR quantifies nucleic acids by comparing the number of amplification cycles and amount of PCR end-product to those of a reference sample, ddPCR enables researchers to directly quantify ...

NEW YORK--(BUSINESS WIRE)--Enzo Biochem, Inc. (NYSE:ENZ), an integrated diagnostics and therapeutics company, today announced the issuance of U.S. Patent No. 10,323,272 entitled Nucleic Acid ...

Modular hybridization probes (M-Probes) have been developed that enable sequence-selective binding of complex nucleic acid targets. The M-probes can target sequences that: are hypervariable at ...

In this new study, scientists have reported a robust method for nucleic acid detection. This method is based on plasmonic sensing of LAMP amplicons through DNA hybridization, termed plasmonic LAMP.

Tools such as Primer3 use matched melting temperatures to rank candidate primer sets, calculated using a two-state model of nucleic acid hybridization.

LUCA GALLUZZI, MAURO MAGNANI, NICK SAUNDERS, CARSTEN HARMS, IAN JAMES BRUCE, Current molecular techniques for the detection of microbial pathogens, Science Progress (1933-), Vol. 90, No. 1 (2007), pp.