The activity of this global transcription factor is in turn modulated by malonyl-CoA, a key fatty acid synthetic intermediate 7. It is surprising then that plsY seems not to be under FapR ...

and its malonyl product is utilized in fatty acid synthesis by FAS. ACC2, on the other hand, with its hydrophobic N-terminus, is associated with the mitochondrial outer membrane, and its malonyl CoA ...