Biopsy followed by gross excision was associated with significantly greater survival outcomes than wide local excision for acral lentiginous melanoma.

Nuclear location of YAP was significantly more prevalent in acral lentiginous and nodular subtypes compared to cases of superficial spreading melanoma (P = .007).

Overall, patients with melanoma of unknown primary, mucosal/ocular melanomas and acral melanomas had the worst outcomes with 5-year survival rates of 0%, 40% and 78%, respectively.

For Southeast Asian patients, acral lentiginous melanoma (ALM) was the most common subtype at 15.34%. Additionally, 33.2% of this population had metastatic melanoma, which was the highest rate ...

Acral lentiginous melanoma, the kind ChatGPT flagged, is especially easy to miss. It often develops in areas not exposed to sunlight, which means people don’t think to look for danger there.

ChatGPT ‘Diagnosis’ “Put a finger down if you asked AI to do a palm reading on you and they told you to get your mole checked because it looks like acral lentiginous melanoma,” says Rin ...

Acral lentiginous melanoma is a subtype of cutaneous melanoma arising from palmar, plantar, or subungual skin. These tumors are characterized by aggressive biology, a low tumor mutational burden (TMB) ...

He also has cases of acral lentiginous melanoma, noting that on the feet or hands, even a small brown dot can be skin cancer. "That's why you need a full skin check from head to toe in your ...

The earliest sign of acral lentiginous melanoma (ALM) is an oddly shaped and discolored patch of skin surrounded by normal skin. The skin may be raised, with black, gray, tan, red, or brown ...

Subungel is a type of acral lentiginous melanoma that develops in non-sun-exposed body areas, such as the palms and soles. "It's more rare, but it's also potentially more aggressive," said Dr ...