A syndrome characterized by severe peptic ulcer disease, gastric acid hypersecretion, and non-beta islet cell tumors of the pancreas was first described by Zollinger and Ellison in 1955.

Your doctor may order imaging tests (CT scan or endoscopic ultrasound) to locate the tumor. Zollinger-Ellison syndrome can be treated with medication to reduce stomach acid and prevent ulcers from ...

The diagnosis of ZES is established by demonstrating fasting hypergastrinemia and hyperacidity in patients suspected of the disease and confirmed by a positive secretion stimulation test when ...