What Kallioniemi and Kononen developed was the tissue microarray (TMA), an ordered array of tissue cores--up to 1,000 of them--on a single glass slide.1 The ...

No writing assistance was utilized in the production of this manuscript. Tissue microarrays (TMAs) have become ubiquitous in the research setting for high-throughput in situ biomarker analysis due ...

such as immunohistochemistry and reverse-phase protein microarrays. Recent advances in performing matrix-assisted laser desorption/ionization imaging mass spectrometry on FFPE tissue makes high ...

Laura Bonetta reports on the use of this technology to analyze other entities, from carbohydrates to tissue samples. The term “microarray analysis” is almost synonymous with the study of gene ...

Tissue/cell processing and embedding Tissue slide sectioning H&E staining Special stains including: PAS, ORO, Trichrome, VVG for elastin, Giemsa Sectioning of thick tissue curls or core punches for ...

This can be detected on the microarray. The first step in using a microarray is to collect healthy and cancerous tissue samples from the patient. This way, doctors can look at what genes are ...

Paraffin microtomy is performed on routine as well as tissue microarray blocks. The thickness of sections ranges from 3-4 um for both H&E staining and immunohistochemistry. We also perform high ...

For the cell biologist, identifying changes in gene expression using DNA microarrays is just the start of a long journey from tissue to cell. We discuss how chip users can first filter noise ...

For connective tissue diseases, the multiplex assay is designed to rapidly detect and identify up to 1275 disease markers per hour. Seamless, microarray-internal calibration and quality control ...