A non-coding RNA lasso catches proteins in breast cancer cells Date: April 24, 2018 Source: Aarhus University Summary: A Danish-German research team has shown that not only the where and when of ...

When CHASERR (CHD2 adjacent, suppressive regulatory RNA) is not functioning normally, it leads to the expression of abnormal levels of CHD2 protein. The findings, which highlight the importance of non ...

The function of non-coding RNA in the cell has long been a mystery to researchers. Unlike coding RNA, non-coding RNA does not produce proteins – yet it exists in large quantities. A research team from ...

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor ...

In patients with this rare disorder, a long non-coding RNA called CHASERR (CHD2 adjacent, suppressive regulatory RNA) is deleted - the "foot" is taken off the "brake" - and CHD2 protein production ...

The vast non-coding portion of the human genome has had ... HAYA is utilizing emerging RNA-targeting modalities, such as modified antisense oligonucleotides (ASOs), to target and inhibit ...

Liquid biopsies are an emerging non-invasive cancer diagnostic that sequences either ... which identifies repetitive noncoding RNAs as well as protein-coding RNA. Researchers at the University of ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 ...

One such non-coding RNA is 4.5SH, found only in small rodents like mice and rats. The 4.5SH gene forms a large cluster of tandem repeats, short lengths of DNA repeated multiple times in a gene ...

Non-coding RNA molecules play an important role in regulation of various processes in the nucleus, but a defined role in regulation of mitochondrial function has not previously been reported.

Figure 1: RNA-seq data uses short reads of mRNA which is free of intronic non-coding DNA. These reads must then be aligned back to the reference genome. Credit: Technology Networks. Early RNA-seq ...