A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

"BAM.IOBIO: A web-based, real-time, interactive sequence alignment file inspector application", appearing online in Nature Methods on Nov. 25, was authored by Chase Miller, Yi Qiao, and Gabor Marth of ...

To date, people have encoded information into DNA the same way nature has, by linking the four nucleotide bases comprising DNA—A, T, C, and G—into a particular genetic sequence.