This work also contributes to growing evidence that information beyond the sequence of RNA, such as chemical modifications, can determine the ultimate fate and function of RNA molecules." ...

By uncovering RNA’s previously unknown function to repair DNA damage, our findings show how RNA may directly contribute to the stability and evolution of the genome. It’s not merely a passive ...

The discovery of the ribosome and the elucidation of its role in gene expression was one of the main achievements of molecular biology in the 1950s and '60s. Early investigations revealed that ...

Inspired by historical work showing that structure plays a role in the function of other classes of RNA such as transfer ... reveal new clues," Xue says. To determine Braveheart's structure ...

They found that this form of regulation, a chemical modification on RNA called m 6 A ... m 6 A modification plays an important role in the function of the nervous system and in sex determination ...

RNA gene scissors (CRISPR-Cas13) are gaining significant attention as a next-generation gene therapy with fewer side effects.

When RNA molecules are synthesized by cells—a critical process in the creation of proteins and other cellular functions—they typically undergo a series of "folding" events that determine their ...

The breadth of functions that RNA performs explains why defective RNA degradation ... Scientists have used cryo-EM microscopy to determine the structure of a key part of the degradation machinery, ...

Ph.D., and his team reveal how the protein SRSF1 possesses the novel function of binding and unfolding complex RNA Guanine-quadruplexes. Present in both DNA and RNA sequences, a G-quadruplex (GQ ...