Figure 1: Discovery of the ligation of ubiquitin to lysozyme, a substrate of the proteolytic system. As indicated before 19, the main lesson from our story is the continued importance of the use ...

Get Instant Summarized Text (Gist) Bacteria can embed themselves permanently in host cells by using specific enzymes to ...

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), ...

Researchers have discovered more about PINK1, a protein that’s directly tied to Parkinson’s disease. A team from Walter and Eliza Hall Institute in Australia has shown how the protein attaches to cell ...

Parkinson's Disease has an early onset form, which affects patients before they reach age 50, and is due to genetic mutations. | Genetics And Genomics ...

Ubiquitin-specific proteases play a critical role in regulating cell death pathways in breast cancer, affecting tumor ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

Researchers say structure reveals many new ways to change PINK1, essentially switching it on, which will be "life-changing" for people with Parkinson’s disease.

This study presents an enhanced nuclease prime editor (uPEn) that significantly improves gene knock-in and knockout ...