The Toll-like receptors (TLRs) fit the definition of pattern-recognition molecules, which were originally postulated to allow the innate immune system to detect the 'molecular signatures' of ...

2,3 In this review, we focus on types of immunodeficiencies in which defects in pattern-recognition receptors and their downstream intracellular pathways predominate. There are four classes of ...

The initiation of the innate immune responses relies on the detection of microbes by multiple pattern recognition receptors. Among these receptors, cyclic GMP-AMP synthase (cGAS) has been ...

Researchers from University of Texas Medical Branch, Galveston, TX, USA review pattern recognition receptors in innate immunity to obligate intracellular bacteria. Host pattern recognition ...

There are different classes of PRRs, including Toll-like receptors (TLRs), NOD-like receptors (NLRs), RIG-like receptors (RLRs), C-type lectin ... examined the pattern of gene expression in ...

which represents a new type of pattern-recognition. Since C. elegans have 274 nuclear hormone receptors, it's possible that the nematode genome contains dozens of these metabolite recognition systems.

Before invaders can be stopped, they must first be detected, and this is accomplished by pattern recognition ... receptors to detect molecular patterns associated with pathogens depends on two ...

Significant advances in understanding the role that the cytokine-mediated JAK/STAT signaling network and pattern recognition receptors (PRRs) play in regulating immune responses and their ...