While humans exploit the venom as a psychedelic, it can cause irritation of the eyes and mouth of humans. Possession of the toad's venom is illegal in California, according to the zoo.

Evidently, toad venom contains other molecules besides 5-MeO-DMT, including a drug called bufotenine (5-HO-DMT), which also has some psychoactive effects, but are far less intense.

“Toad medicine is watching the movie in 3-D,” added Dr. Sandoval, who owns a ranch in Sonora, where he raises the toads and charges $500 for a venom ceremony.

Why Is Everyone Smoking Toad Venom? How an illegal amphibian-venom-derived psychedelic became the loudest whisper at a dinner party near you. By Alex Kuczynski Published: Jan 20, 2022 9:00 AM EST ...

They compared it to LSD as well as existing drugs that target 5-HT 1A, and found that the toad venom compound had a similar antidepressant and anti-anxiety effect – without getting the mice high.

Toad-stones “touching any part envenomed by the bite of a rat, wasp, spider or other venomous beast, ceases the pain and swelling thereof.” This hermetic treatment seems to have had some value.

It’s become a toad-al nightmare out west.. The National Park Service has put out a PSA pleading with nature-goers to stop licking toads in the wild to get high off their gland-secreted ...

Previously HGTV's Christina Hall admitted to smoking the toad's venom to reduce anxiety. "Smoking the bufo toad venom is a life-changing experience and different for every person.

Psychedelic toad venom, also known as 5-MeO-DMT, is a potent hallucinogen derived from the Colorado River toad. When vaporized and inhaled, it can lead to powerful, albeit short-lived, psychedelic ...