The implementations of high-throughput genetic technologies, such as oligonucleotide microarrays ... To get as many high-quality sections from one multi-tissue block as possible, it is advisable ...

Therefore, we investigated the number of sections that are needed to obtain more than 90% of scorable cores from a tissue microarray block. For that purpose, we sectioned one of the two tissue ...

Tissue microarrays (TMAs) have become ubiquitous ... Methods that can be applied to whole-tissue sections are applicable to TMAs including DNA-, RNA- and protein-based assessments.

These delicate sections are floated out on a water bath and picked up on a glass slide. Paraffin wax is dissolved from the tissue block by using solvents. Then the tissues are stained with dyes ...

For this, the tissue sample is preserved and subsequently dehydrated and embedded in paraffin blocks. Further on, thin tissue sections of ... This so-called Tissue Microarray (TMA) is a tissue ...

A substantial archive of paraffin ... quality control for tissue sections with project specific morphology case reviews and oversee and provide longitudinal follow-up of clinical outcomes linked to ...

Formalin-Fixed Paraffin Embedded (FFPE ... extensive inventory of pathologist-reviewed FFPE tissue blocks, slides, curls, cores, and tissue microarrays from both normal and diseased subjects ...

Coupling proteomic investigations with the retrospective pathology information available from archival formalin-fixed, paraffin-embedded ... such as tissue microarrays, feasible.

All patient cases underwent a centralized review to determine tumor content (reported as percentage of total cell number) and select the area of the paraffin block for tissue microarray (TMA) ...

Total RNA was extracted from FFPE tumor samples using the Roche High Pure RNA Paraffin Kit (Roche ... assay is performed on FFPE tissue and, therefore, is easily applied in current medical practice.