Tissue microarrays combines tens to hundreds of paraffin-embedded tissue cores into a single paraffin block. It is a practical and highly effective technique for high-throughput analyses of various ...

To study tissue samples from multiple patients, researchers use tissue microarrays (TMAs), a technology in which hundreds of tissue cores are arranged on a single glass slide for analysis by ...

Kononen et al. (2) popularized microarray technology by describing a single paraffin receiver block that contains ≤1000 different yet uniformly-sized tissue samples.

They have a method of transferring proteins from a formalin-fixed, paraffin-embedded (FFPE) tissue section to a stack of membranes that is probed with antibodies to detect individual epitopes.

Immunostaining of tissue microarray sections and conventional full sections of each tumor were performed using well-characterized prognostic markers (estrogen receptor ER, progesterone receptor PR ...

To promote good ribbon generation, the paraffin block needs to be sufficiently hard to enable the sections to be cut on the microtome. This is routinely achieved by placing the paraffin blocks on ice, ...

Background: Cancer stroma plays a critical role in tumorigenesis. Microarrays are widely used to study gene expression patterns in tumor frozen tissue to explore tumorigenesis and predict recurrence.

Microarray-based gene expression profiles to predict ELISA-derived uPA and PAI-1 levels in breast cancer biopsies: A comparison between fresh frozen (FF) and formalin-fixed, paraffin-embedded (FFPE) ...

The Thermo Scientific Cool Cut specimen clamp maintains block temperature for more consistent, better quality sections.