PK Modulator Shows Promise in Thalassemia — In small study, mitapivat increased hemoglobin in 80% of non-transfusion-dependent patients by Mike Bassett, Staff Writer, MedPage Today August 17, 2022 ...

Gene therapy that alters hemoglobin genes may be an answer to curing sickle cell disease (SCD) and beta thalassemia. These two common life-threatening anemias afflict millions of individuals ...

Both sickle cell disease and thalassemia are caused by mistakes in the genes that carry hemoglobin, the protein in red blood cells that carry oxygen.

Ada, 9, was born with beta thalassemia major, a genetic blood condition that causes her blood cells to lack sufficient hemoglobin, the blood protein that carries oxygen — thereby suffocating her body ...

Thalassemia, an inherited blood disorder affecting hemoglobin, has 4,361 registered patients in India, with the Health Ministry actively monitoring cases and providing financial support to the affecte ...

Researchers have developed a proof-of-concept treatment for blood disorders like sickle cell disease and beta-thalassemia that could raise hemoglobin levels by activating production of both fetal ...

“Beta thalassemia can be a very serious disease that often goes undetected before it is too late in India and many other parts of the world,” said Tulika Seth, MD, Founding Trustee and ...

Beta thalassemia describes a condition of the blood characterized by abnormal hemoglobin in the red blood cells. This abnormal hemoglobin is reduced in its capacity to transport oxygen around the ...

Beta-thalassemia is an inherited disorder of the blood that affects the hemoglobin inside red blood cells. The condition is caused by an abnormality in the production of the beta globin chain ...

Patients with non-transfusion-dependent beta-thalassemia should be considered for interventions targeting ineffective erythropoiesis and anemia when hemoglobin levels are <10 g/dL ...

HYDROPS fetalis associated with hemoglobin Barts is believed to represent the homozygous state of α thalassemia. Ten cases occurring in Chinese families in Indonesia, Malaya and Hong Kong, 1 in a ...

Hemoglobin-S proportions of α-thalassemia-hemoglobin-S double heterozygotes were depressed. Cases of a-thalassemia-hemoglobin-E disease reported by Tuchinda et al. 10 showed similar features.