Li Ding, Feng Chen and colleagues report a pan-cancer analysis using a new computational tool, HotSpot3D, to identify mutational hotspots in the encoded three-dimensional protein structure, which ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, ...

DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease ...

All living organisms encode the amino acid sequences of proteins as nucleotide sequences (genetic information) in their ...

Structure of a eukaryotic CRISPR-Cas homolog, Fanzor2, shows its promise for gene editing. ScienceDaily . Retrieved July 12, 2025 from www.sciencedaily.com / releases / 2024 / 10 / 241001132939.htm ...

Researchers at the Universitat Autònoma de Barcelona (UAB) have determined the structure of of amyloid fibres formed by the protein hnRNPDL-2, implicated in limb-girdle muscular dystrophy type 3 ...

An unusual DNA structure may hold the key to treating one of the deadliest cancers affecting women, which claims more than ...

DeepMind’s chief executive, Demis Hassabis, said the AI had “provided structural biologists with this powerful new tool now, where you can look up a 3D structure of a protein almost as easily ...

As the first crystal structure of this type, the researchers say it will also be useful as a model for other targets in the genome, besides the insulin gene, which form this shape of DNA.

Medusa-structure of gene regulatory network: Dominance of transcription factors in cancer subtypes. Your friend's email. Your email. I would like to subscribe to Science X Newsletter.

Scientists use lab-grown human brain tissue to identify neural abnormalities in Pitt-Hopkins Syndrome and show gene therapy tools can rescue neural structure and function. In a study published May ...