LSD's ability to fit in and let the receptor's "lid" close over it depends on the specific chemical structures of both the drug and the receptor. When the team exposed cells with mutant receptors ...

Scientists at the University of California, Davis have developed a new drug related to LSD that retains the psychedelic’s ...

Scientists have long known that psychedelics like LSD can help the brain grow new connections. These drugs promote something ...

A team of researchers at the University of California, Davis, made small tweaks to the molecular structure of lysergic acid diethylamide (LSD) to see if it could be turned into an effective brain ...

LSD activates the first one more ... and some other team members had recently solved the crystal structure of the 5HT2b receptor. They used that structure to model the 5HT2a until Roth’s group worked ...

Ellman, meanwhile, created a method to synthesize a family of molecules called tetrahydropyridines, which is core to the structure of LSD. Along with Shoichet, they built out the 75 million-strong ...

Looking at the molecular structure of LSD and how it fits like a glove into the pocket of serotonin receptors, Olson and his team surmised that if they clipped off two specific atoms from LSD ...

LSD has always been a source of fascination for Olson because of its outstanding ability to form and strengthen neural pathways. “We have consistently found that LSD is among the best ...

LSD is a potent, long-lasting psychoactive drug. In part, it’s derived from a fungus that grows on rye and other grains. The synthetic drug has a chemical structure similar to serotonin ...