Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface. Cell Reports, 2021; 34 (13): 108924 DOI: 10.1016/j.celrep.2021.108924 ...

Osaka, Japan - Streptococcus pyogenes is one of the most important bacterial causes of human skin infections. If S. pyogenes invades deep into the tissue, it can cause life-threatening illnesses ...

Hirose, Y., et al. (2021) Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface. Cell Reports. doi.org/10.1016/j.celrep.2021.108924.

Streptolysin S (SLS) is a potent cytolytic toxin and virulence factor that is produced by nearly all Streptococcus pyogenes strains. Despite a 100-year history of research on this toxin, it has ...