Amide bonds are important functional groups in medicinal chemistry and account for roughly 16% of all reactions performed in drug-discovery research. Some amide bond reactions using ...

The first known synthesis of ethyl methylphenylglycidate was reported in 1905 by Rainer Ludwig Claisen at the University of Berlin in a lengthy article titled “About some syntheses using sodium amide” ...

In proteins, amino acids are held together by amide bonds. These bonds are long-lived and are robust against changes in temperature, acidity, or alkalinity. Certain medicines make use of reactions ...

Alkene Isomerisation Catalysed by a Superbasic Sodium Amide. Journal: Angewandte Chemie International Edition Published: 2024-06-17 DOI: 10.1002/anie.202407262 Affiliations: 2 Authors: 6. Go to ...