Two high-frequency, coding, non-synonymous Single Nucleotide Polymorphisms (SNPs) have been described in the HER2 gene. The first (Ile655Val) is related to a residue in the trans-membrane domain, the ...

Single nucleotide polymorphisms (SNPs) are variations in a genome’s base pair in a DNA sequence, and occur in approximately 1 out of 800 base pairs. These occur when a single nucleotide is ...

Our aim was to determine whether single nucleotide polymorphisms in TLR6 are associated with altered immune responses to lipopeptides and whole mycobacteria.

Endothelial vulnerability is a potential risk factor for complications after allogeneic stem-cell transplantation (alloSCT). The CD40/CD40 ligand (CD40L) axis contributes to inflammatory diseases and ...

This review discusses the causes, pathogenesis, and clinical management of membranoproliferative glomerulonephritis, which accounts for 7 to 10% of biopsy-confirmed glomerulonephritis cases. Curren ...

Scientists have developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and send the results in real time to an electronic device. The chip is ...

The paper reports a new version of the Cardean CRISPR-Chip called SNP-Chip that can rapidly detect and quantify single nucleotide polymorphisms (SNPs), or point mutations, in unamplified, genomic ...

There were no other associations between single -nucleotide polymorphisms and the efficacy of MTX treatment. CONCLUSIONS The MTHFR 677CC and GGH 401TT and CT genotypes were associated with a reduction ...