Discover the current pipeline candidates advancing through the clinic for the treatment of sickle cell disease.

For people with SCD, hemoglobin S (a mutated protein that transports oxygen) causes red blood cells to become curved (sickle-shaped) and stiff. This disrupts how easily red blood cells and the oxygen ...

Sickle cell disease is a genetic disease that can’t be prevented, ... SCD is a series of inherited disorders that affect hemoglobin, the major protein that carries oxygen in red blood cells.

Sickle cell disease can lead to a severe complication known as acute chest syndrome (ACS), but the underlying mechanisms are ...

Hemoglobin (Hb) is the protein in the red blood cell that carries oxygen. Sickle cell disease occurs when someone inherits an abnormal gene for hemoglobin, causing sickle hemoglobin or HbS. Producing ...

Gene therapy for sickle cell disease may help improve a major contributing factor to stroke risk in patients, reports a new ...

The Food and Drug Administration has granted Orphan Drug designation to KIND Pharmaceutical’s AND017 for the treatment of sickle cell disease (SCD).

SAN DIEGO — Etavopivat reduced the annualized vaso-occlusive crises rate vs. placebo for people with sickle cell disease, according to study data presented at ASH Annual Meeting and Exposition ...

Sickle cell disease (SCD) is a genetic disorder characterized by abnormal hemoglobin causing red blood cells to deform. Nutrition is crucial in managing SCD, as malnutrition and micronutrient ...

Sickle cell disease (SCD) is a group of painful and life-threatening genetic disorders that affect hemoglobin, the major protein that carries oxygen in red blood cells. It occurs in nearly 100,000 ...

Hydroxyurea, approved for sickle cell disease over two decades ago, remains the cornerstone preventive therapy. It works by increasing production of fetal hemoglobin, which prevents red blood ...

There's new hope for people with sickle cell disease which affects mainly African Americans. It's gene therapy research at Children's Hospital of Philadelphia that's being called a game changer.