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Serum protein electrophoresis (SPEP) is a clinical tool used to screen for monoclonal gammopathy, thus it is a critical tool in the evaluation of patients with multiple myeloma. However, SPEP ...
In the same samples analyzed by SPEP, either daratumumab and daratumumab plus anti-idiotype complex could be identified at 100 µg/ml in 3 of 10 samples and by 200 µg/ml in 10 of 10 samples.
Audit of Use and Overuse of Serum Protein Immunofixation Electrophoresis and Serum Free Light Chain Assay in Tertiary Health Care. American Journal of Clinical Pathology , 2016; aqw026 DOI: 10. ...
Serum protein electrophoresis (SPEP) did not reveal an M-protein. Serum and urine IEP demonstrated a monoclonal λ Bence Jones protein. A 24-hour urine specimen contained 6.7 g of protein, ...
The researchers also highlighted the utility of combining serum free light chain testing with serum protein electrophoresis to improve detection rates, as 1 in 5 patients will have light chains only.
When using serum protein electrophoresis as the screen, the main causes for false positives include the presence of fibrinogen and genetic variants of normal serum proteins. When capillary ...
Serum protein electrophoresis and immunofixation showed that the level of monoclonal IgG kappa was 2840 mg per deciliter. A diagnosis of MGUS was made on the basis of the unremarkable findings on ...