Adult skeletal muscle possesses a remarkable regenerative ability. This depends on satellite cells that reside adjacent to and beneath the basal lamina of myofibres and function as adult muscle ...

In mature skeletal muscle, satellite cells are usually present in a dormant state. Upon stimulation after muscle injury, satellite cells are rapidly activated and proliferate repeatedly.

The transcription factor Prox1 is essential for satellite cell differentiation and muscle fibre-type regulation. Nature Communications , 2016; 7: 13124 DOI: 10.1038/NCOMMS13124 Cite This Page : ...

Feodor Price grew human skeletal muscle organoids from myoblasts, which differentiated into mature muscle cells and de-differentiated into expandable and novel satellite-like cells. In this microscopy ...

Our skeletal muscles, which link to bones and enable us to move, have a remarkable ability to regenerate after they've suffered an injury. Scientists have now developed a cutting edge microscopy tool ...

Harvard stem cell biologists have pioneered a groundbreaking 3D organoid culture method for generating large numbers of adult skeletal muscle satellite cells, also known as muscle stem cells, in ...

Satellite cells are stem cells found in skeletal muscles. While transplantation of such muscle stem cells can be a potent therapy for degenerative muscle diseases such as Duchenne muscular ...

Sambasivan R, Yao R, Kissenpfennig A, et al. (2011) Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration. Development. doi: 10.1242/dev.067587. Chargé SB ...

However, when a muscle is damaged, satellite cells start to replicate themselves (proliferation) and turn into muscle cells (differentiation). "When a muscle is damaged, we can use this technology ...

Working Muscle. In a world first, biomedical engineers from Duke University have created the first functioning human skeletal muscle from pluripotent stem cells, which are capable of producing any ...