In a new paper published in the journal Nature Methods, researchers at UC Santa Cruz introduce the first-ever method for analyzing RNA sequencing data genome-wide using a “pantranscriptome,” which ...

First, the pipeline identifies which areas of the genome the RNA sequencing data comes from, including the splice sites, and marks those points on the pangenome reference.

The heterogeneity of isoform level m 6 A RNA methylation in single cells is unclear. The authors characterize m 6 A at both single-cell and isoform level through ONT long-read sequencing on single ...

The development of high-throughput DNA sequencing methods provides a new method for mapping and quantifying transcriptomes — RNA sequencing (RNA-Seq). This article explains how RNA-Seq works ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

Li S, Tighe SW, Nicolet CM et al. Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study. Nat. Biotechnol. 32(9), 915-925 (2014); Wang C, Gong ...

PolyA-RNA-seq: Capture of coding RNAs. Requires intact RNA. Full-length transcripts are captured. Recommended read depth is 15-30 million reads/sample although deeper sequencing may be required in ...

Direct Sequencing Of DNA, RNA Using Novel Technique. ScienceDaily. Retrieved June 4, 2025 from www.sciencedaily.com / releases / 2008 / 01 / 080128113219.htm. Wiley-Blackwell.

This additional evidence improved the classification of LB and LP in 33.9% of cases, leading to reclassification to B or P. Furthermore, VUS was reclassified as LB or B in 45.5% of cases.

A clinical research team from the University of Hong Kong (HKUMed) has used amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal ...

It is designed to facilitate single-cell RNA sequencing by eliminating the need for complex, expensive instrumentation and microfluidic consumables. The company launched its first kit in July 2022.

RNA diversity in human tissues mapped with emerging sequencing technology. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2022 / 08 / 220803112544.htm ...