Because RNA pol II transcribes ... the purposes of polymerase studies - although recreational mushroom hunters should beware! Thus, while eukaryotic transcription is far more complex than ...

Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

J Biol Chem 2022, 102433. Richter, WF; Nayak, S; Iwasa, J; Taatjes, DJ. The Mediator complex as a master regulator of transcription by RNA polymerase II. Nat Rev Mol Cell Biol 2022, 23: 732 - 749.

"When SPT5 is lost, this ARMC5 mechanism will recognize RNA polymerase II and then eliminate this defective transcription complex." The findings may also inform the understanding of the ...

Three different types of RNA polymerase exist in eukaryotic ... Termination of pol II transcripts, however, is more complex. Transcription of pol II genes can continue for hundreds or even ...

Single-Molecule Footprinting reveals that RNA polymerase II (Pol II) occupancy is infrequent at mouse promoters. This results from a combination of higher Pol II turnover and lower transcription ...

In Eukarya, RNA Polymerase II (Pol II) transcription is a highly regulated process ... or more directly by facilitating the assembly and function of the preinitiation complex (PIC). It is now widely ...