In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read like a recipe to build a protein. But there's more to the story. Some RNA ...

Using CRISPR-Cas13 to edit RNA and avoid off-target activity, the researchers systematically profiled nearly 6,200 gene pairs of long noncoding RNAs (lncRNAs) and nearby protein-coding genes ...

RNA vaccines are a new class of vaccines that are composed of an mRNA sequence coding for a pathogen-specific protein (antigen). Once expressed in the body, the target antigen is recognized by the ...

RNA sequences involved in regulating gene expression identified Date: July 29, 2020 ... Unlike coding RNA, non-coding RNA does not produce proteins -- yet it exists in large quantities.

In the human transcriptome, along with around 25 thousand sequences of coding RNA (i.e. the sequences involved in the synthesis process), an even larger number of non-coding RNA sequences can be ...

Profiling noncoding repetitive RNA sequences improves the sensitivity of liquid biopsy diagnostic tests for early stage cancers. As cancer is most treatable in its early stages, developing diagnostic ...

These RNA molecules are named non-coding RNAs (ncRNAs) ... regulate gene expression by binding to complementary sequences on target mRNAs, leading to mRNA cleavage, ...

A strategy that analyzes the structural properties of RNA could help identify regions that are promising targets for antiviral drugs.

Kim’s lab developed an RNA liquid biopsy platform that detects both protein-coding RNA and RNA dark matter in the blood, ... RNA liquid biopsy technology developed by the Kim lab aims to detect cancer ...

But RNA can also regulate gene activity by way of non-coding RNAs, whose genetic sequence is not used to generate proteins. One such non-coding RNA is 4.5SH, found only in small rodents like mice ...

Figure 1: RNA-seq data uses short reads of mRNA which is free of intronic non-coding DNA. These reads must then be aligned back to the reference genome. Credit: Technology Networks. Early RNA-seq ...

Not junk, after all. Using CRISPR-Cas13 to edit RNA and avoid off-target activity, the researchers systematically profiled nearly 6,200 gene pairs of long noncoding RNAs (lncRNAs) and nearby ...