The team’s first version of a flow-based peptide synthesis machine, reported in 2014, sped up the process to about three minutes per peptide bond. In their latest effort, the researchers hoped to make ...

The flow system is 10 to 100 times as fast as batch-based solid-phase peptide synthesis methods currently used, Pentelute says. If the Amidator worked nonstop for a year, it could create tens of ...

Flow-through peptide synthesis and cell-based assays on Teflon-coated paper. by Angewandte Chemie (Phys.org) —The synthesis of peptides and proteins is an extremely complex matter, ...

Vapourtec’s R-Series flow chemistry system, equipped with a UV-150 photochemical reactor, has been cited in research by scientists* at Novo Nordisk in the C-terminal α-amination of peptides and ...

The Peptide-ExplorerLT ™ is designed for scientists who need to optimize and explore linear peptide synthesis. The product is a high-spec flow chemistry system that uses continuous flow. The product ...

Covina, Jan. 05, 2023 (GLOBE NEWSWIRE) -- Peptide Synthesis and its applications are increasing due to development in bioengineering and biotechnology sector and also used for various research ...

The method, called automated fast-flow peptide synthesis, adds amino acids to the growing peptide chain at a rate of 2.5 min per residue. This means their machine, ...

The new system, described in a paper (“Rapid Total Synthesis of DARPin pE59 and Barnase”) in ChemBioChem, could have a major impact on peptide drug development, says Bradley Pentelute, Ph.D ...

Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections. To ...

On small scale (250 μM), this protocol was successfully used in batch for the synthesis of the GLP-1R agonist, GLP-1(7-36), one example of an important class of therapeutic peptides that includes the ...

Image Credit: VAPOURTEC Ltd. Published in a paper in Nature Communications entitled ‘Photochemically-enabled, post-translational production of C-terminal amides’, the process involved three steps: ...