This article was originally published with the title “ The Three-Dimensional Structure of an Enzyme Molecule ” in Scientific American Magazine Vol. 215 No. 5 (November 1966), p. 78 doi:10.1038 ...

The structure of a vancomycin biosynthetic enzyme in complex with a substrate analog, and with molecular oxygen bound in its active site, supports the idea that cofactor-independent oxygenases act ...