2007;27(8):509-531. Antiretroviral drugs (ARVs) can be divided into four different classes according to their modes of action: nucleoside or nucleotide reverse transcriptase inhibitors (NRTIs or ...

Many of the nucleoside antibiotics exhibit their activity only after conversion into their nucleotide form (mono- or triphosphate) once inside the cell. A number of nucleoside analogues which were ...