(B) Sequencing by hybridization. To resequence a given base, four features are present on the microarray, each identical except for a different nucleotide at the query position (the central base ...

In its basic form (i.e., hybridization, stringent washing ... probes thus requires nothing more than selecting 15–21 long nucleotide allelic sequences centered on the polymorphic nucleotide.

Comparative Genomic Hybridization (CGH ... but struggles to detect smaller mutations like single nucleotide polymorphisms ...