Although RCC1 has been shown to bind directly with the nucleosome, the molecular details of this interaction were not known. Here we determine the crystal structure of a complex of Drosophila RCC1 ...

DNA lesions are repaired by a cut-and-remove process called nucleotide excision repair ... on the DNA repair process (Mol Cell Biol 2000, 20:9173-9181). A nucleosome structure was assembled by mixing ...

This technique, called X-ray crystallography, yields precise information about the position of each and every amino acid and nucleotide in the molecules ... like to look for the missing link—a ...

1 The verdict: several dinucleotide sequences, because of their inherent bendability, can be used to predict roughly 50% of nucleotide positions. The work, may lead to better prediction of nucleosome ...