"The importance of deoxyribonucleic acid (DNA) within living cells is undisputed" (Watson & Crick, 1953). This opening sentence of James Watson and Francis Crick's second major paper, published ...

Nucleic acid-based techniques, such as polymerase chain reaction (PCR) and DNA sequencing, are widely used in molecular diagnostics. These methods allow for the detection and identification of ...

In 1919, Russian biochemist, Phoebus Levene proposed that nucleic acids are made up of nucleotides, which are composed of one of the four bases – A (adenine), T (thymine), G (guanine) and C ...

TNAs [ (L)-α-threofuranosyl oligonucleotides] containing vicinally connected (3′→2′) phosphodiester bridges undergo informational base pairing in antiparallel strand orientation and are capable of ...

Spherical nucleic acids (SNAs) are structures that are made by taking nanoparticles and synthesizing short snippets of DNA or RNA that are terminated with groups that can chemically bond to the ...

"The importance of deoxyribonucleic acid (DNA) within living cells is undisputed" (Watson & Crick, 1953). This opening sentence of James Watson and Francis Crick's second major paper, published ...